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Mayo Clinic and TGen ID potential targets for the most-deadly form of pancreatic cancer

A team of researchers led by Mayo Clinic and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified specific potential therapeutic targets for the most aggressive and lethal form of pancreatic cancer. In what is believed to be the most comprehensive analysis of adenosquamous cancer of the pancreas (ASCP), the […]

Cancer Projects to Diversify Genetic Research Receive New Grants

The New York Genome Center awarded six cancer research grants this week as part of an initiative examining the role of race and ethnicity in major types of cancer. The projects will investigate a variety of cancers including pancreatic, colorectal and endometrial cancer in African-Americans; lung cancer in Asian-American patients; breast and prostate cancer in […]

UH researcher discovers susceptibility genes for pancreatic cancer

Six novel susceptibility genes for pancreatic cancer risk have been identified by University of Hawaiʻi Cancer Center researcher Lang Wu. The study was published in Cancer Research by the American Association for Cancer Research. “Our discovery of novel candidate susceptibility genes associated with pancreatic cancer will allow us to better understand the biology and genetics of this deadly malignancy, and help us […]

Diabetes increases risk for pancreatic cancer, study finds

Older adults with diabetes are nearly three times as likely to develop pancreatic cancer than the general population, according to an analysis published Thursday by JAMA Oncology. The link between diabetes and pancreatic cancer increases to seven-fold for people with the relatively rare Type 3C diabetes, which is caused by pancreatic conditions, the researchers said. The […]

COMBAT study preliminary results show response of 32% in treatment of pancreatic tumors

Working with an international team of researchers, HonorHealth Research Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, were instrumental in one of the first clinical trials showing how pancreatic cancer patients can benefit from immunotherapy, according to a four-year study published in a premier scientific journal, Nature Medicine. The […]

The first mouse model of human pancreas cancer subtypes

Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help researchers investigate why some pancreatic cancers are more aggressive than others and what causes them to progress, paving the way to […]

Study suggests new potential strategy to fight against pancreatic cancer

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature Metabolism, also suggest a new potential strategy against pancreatic cancer by identifying critical components of metabolic cross talk between cells that might be attacked […]

Ipsen scores FDA fast-track for Onivyde in first-line pancreatic cancer

The FDA designation will review the use of Onivyde (liposomal irinotecan) in combination with 5- fluorouracil/leucovorin (5-FU/LV) and oxaliplatin (OX), also known as Nalirifox, in patients with previously untreated, unresectable, locally advanced and metastatic pancreatic ductal adenocarcinoma (PDAC). The fast-track programme aids the development and also expedites the review of drugs that are designed to treat serious […]
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