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A DNA mutation that occurs frequently in the development of many pancreatic tumors appears to make these cancers vulnerable to an existing type of drug known as PARP inhibitors, according to a new study from scientists in the Perelman School of Medicine at the University of Pennsylvania. The discovery, published in Science Advances, centers on a […]

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest how a compound derived from the thunder god vine — an herb used in China for centuries to treat joint pain, swelling and fever — is able to kill cancer cells and […]

esearchers say they’ve identified a way to disrupt a process that promotes the growth of pancreatic cancers — one of the most difficult and deadly cancers to treat. The team, led by scientists at Georgetown Lombardi Comprehensive Cancer Center and including investigators from Lawrence Livermore National Laboratories, STCube and Fluidigm, published their findings today in […]

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell. The study addresses pancreatic ductal adenocarcinoma (PDAC), the deadliest cancer of the pancreas with a five-year […]

South Dakota’s State Capitol turns purple Sunday (Nov. 1) to honor those who have died from, as well as those who have survived, pancreatic cancer. The seventh annual Light the Capitol Purple for Pancreatic Cancer Awareness ceremony starts at 3pm CT in the Capitol Rotunda in Pierre. Organizer John Moisan of Fort Pierre is a […]

Many patients with pancreatic cancer have only about a 10% chance of survival within five years of their diagnosis because they tend to become resistant to chemotherapy, past studies have indicated. A “time machine” that Purdue University engineers designed to observe pancreatic cancer behavior over time suggests a new drug testing approach that could help scientists better […]

Clinical trials should not be viewed as a last resort for patients with metastatic pancreatic cancer, explained Allyson Ocean, MD, who added that even frontline standards of care should be considered after exhausting all available study options. “There are plenty of clinical trials available for your patients. Clinical trials should always be the first consideration […]

Pancreatic cancer is a serious and often fatal disease, but a September study published in Practical Radiation Oncology explores a new advancement in radiation therapy that may provide a better treatment option for some patients. Along with his colleagues, Michael Chuong, MD, study author and a board-certified radiation oncologist with the Miami Cancer Institute, studied 35 […]

Weight-loss surgery significantly reduces the risk of pancreatic cancer in obese people with diabetes, a new study finds. For the study, the researchers analyzed 20 years of data from 1.4 million people, including more than 10,000 who’d had weight-loss surgery. About three-quarters of those who had weight-loss surgery were women. People who’d had weight-loss surgery […]

Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease. […]