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A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers. The researchers targeted their immunotherapy approach to alterations in the common cancer-related p53 tumor suppressor gene, the RAS tumor-promoting oncogene or T-cell receptor […]

UC Davis professor of biomedical engineering and hematology/oncology Julie Sutcliffe has been elected to the American Institute for Medical and Biological Engineering (AIMBE) College of FellowsJulie Sutcliffe, UC Davis professor of biomedical engineering and hematology/oncology Julie Sutcliffe, UC Davis professor of biomedical engineering and hematology/oncology Sutcliffe was elected by members of the College of Fellows […]

In recent years there has been a movement toward so-called precision medicine in cancer treatment. For pancreatic cancer patients and others with different forms of cancer, precision medicine means using drugs to target specific mutations in genes in hopes of slowing disease progression. For some cancers, such as certain forms of lung cancer, this targeted […]

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also effective against triple-negative breast […]

CAR T cells modified to recognise CEACAM7 were able to eliminate pancreatic ductal adenocarcinoma cells in a late-stage model without toxic effects on healthy tissue. Researchers have identified and validated a promising protein target that could be used in novel chimeric antigen receptor (CAR) T-cell therapies for pancreatic cancer. According to the team, this is […]

A DNA mutation that occurs frequently in the development of many pancreatic tumors appears to make these cancers vulnerable to an existing type of drug known as PARP inhibitors, according to a new study from scientists in the Perelman School of Medicine at the University of Pennsylvania. The discovery, published in Science Advances, centers on a […]

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest how a compound derived from the thunder god vine — an herb used in China for centuries to treat joint pain, swelling and fever — is able to kill cancer cells and […]

esearchers say they’ve identified a way to disrupt a process that promotes the growth of pancreatic cancers — one of the most difficult and deadly cancers to treat. The team, led by scientists at Georgetown Lombardi Comprehensive Cancer Center and including investigators from Lawrence Livermore National Laboratories, STCube and Fluidigm, published their findings today in […]

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell. The study addresses pancreatic ductal adenocarcinoma (PDAC), the deadliest cancer of the pancreas with a five-year […]

South Dakota’s State Capitol turns purple Sunday (Nov. 1) to honor those who have died from, as well as those who have survived, pancreatic cancer. The seventh annual Light the Capitol Purple for Pancreatic Cancer Awareness ceremony starts at 3pm CT in the Capitol Rotunda in Pierre. Organizer John Moisan of Fort Pierre is a […]