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Mutant Gene-Targeted Immunotherapy Approach Developed

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers. The researchers targeted their immunotherapy approach to alterations in the common cancer-related p53 tumor suppressor gene, the RAS tumor-promoting oncogene or T-cell receptor […]

Molecular imaging scientist recognized as one of the top biomedical engineers in U.S.

UC Davis professor of biomedical engineering and hematology/oncology Julie Sutcliffe has been elected to the American Institute for Medical and Biological Engineering (AIMBE) College of FellowsJulie Sutcliffe, UC Davis professor of biomedical engineering and hematology/oncology Julie Sutcliffe, UC Davis professor of biomedical engineering and hematology/oncology Sutcliffe was elected by members of the College of Fellows […]

Drug Developed by Georgia State Researcher Is Promising Against Pancreatic and Breast Cancers Drug Developed by Georgia State Researcher Is Promising Against Pancreatic and Breast Cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also effective against triple-negative breast […]

CAR T cells targeting the CEACAM7 protein show promise in pancreatic cancer

CAR T cells modified to recognise CEACAM7 were able to eliminate pancreatic ductal adenocarcinoma cells in a late-stage model without toxic effects on healthy tissue. Researchers have identified and validated a promising protein target that could be used in novel chimeric antigen receptor (CAR) T-cell therapies for pancreatic cancer. According to the team, this is […]

Disrupting the Cellular Process That Promotes Pancreatic Cancer’s Deadly Growth

esearchers say they’ve identified a way to disrupt a process that promotes the growth of pancreatic cancers — one of the most difficult and deadly cancers to treat. The team, led by scientists at Georgetown Lombardi Comprehensive Cancer Center and including investigators from Lawrence Livermore National Laboratories, STCube and Fluidigm, published their findings today in […]

Nerves keep pancreatic cancer cells from starving

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell. The study addresses pancreatic ductal adenocarcinoma (PDAC), the deadliest cancer of the pancreas with a five-year […]
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